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HITS-Bio: High-Throughput Bioprinting for Scalable Tissue Fabrication
HITS-Bio (High-throughput Integrated Tissue Fabrication System for Bioprinting), develop from Dr. Ibrahim Ozbolat’s lab, has emerged as a system that integrates advanced digitally-controlled nozzle arrays (DCNA) to enable rapid, scalable bioprinting of tissue spheroids with improved accuracy and speed. The HITS-Bio PlatformHITS-Bio leverages a multi-array nozzle system, the platform achieves: The system’s DCNA allows simultaneous…
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Unveiling the Impact of Hypodermis on Gene Expression in 3D Bioprinted Skin Models
Introduction: The development of full-thickness human skin models that accurately replicate all three structural layers of human skin—epidermis, dermis, and hypodermis—continue to be pushed forward. Traditionally, 3D skin models used for research and development focused only on the epidermis or epidermis/dermis combinations, often overlooking the hypodermis. Earlier this year though, we covered how WFIRM published…
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Bioprint FirstAid: In Situ Bioprinting In Space to Benefit Earth and Beyond
The “Bioprint FirstAid,” is a new handheld in situ bioprinter designed for first-aid wound treatment in space. This device, a project by the German Space Agency in collaboration with OHB System AG and Technische Universität Dresden, printed objects both on earth and actually on the space station. The fact that they did printing in space…
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Exploring Dynamic Interface Printing: A New Approach to Rapid 3D Printing in Biofabrication
3D printing has come a long way since its beginnings, but the field is still rapidly evolving. A new technique called Dynamic Interface Printing (DIP) recently published in Nature brings a fresh approach to printing complex, centimeter-sized 3D structures in mere seconds. This technique has broad implications for industries like healthcare, aerospace, and bioprinting, where…
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POSTECH 3D Bioprinting of a Biomimetic Urinary Bladder Model
Bladder dysfunction can cause significant medical issues, including urinary incontinence and renal failure, yet the ability to accurately model and treat such problems has long been limited by the lack of realistic bladder models. Traditional in vitro (lab-based) models often fail to replicate the complex functions and structures of the human bladder. This gap in…
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Bioprinted Blood Vessels Offer New Approach into Brain Tumor Treatment
Researchers have developed bioprinted blood vessels using human cells to better understand and treat aggressive brain tumors like glioblastoma. This approach aims to replicate the brain’s vascular networks more accurately, providing a better platform for studying tumor behavior and testing therapies. Fig: llustrating the Assembly of a 3D-bioprinted System. Credit: Advanced Healthcare Materials (2024). DOI: 10.1002/adhm.202401876 Challenges…
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xolo Partners with Rousselot to Enhance Volumetric Bioprinting with X-Pure GelMA
German 3D printing innovator xolo has entered into a co-branding agreement with Rousselot, a leading collagen and gelatin brand under Darling Ingredients. This collaboration aims to integrate Rousselot’s X-Pure Gelatin Methacrylate (GelMA) solution into xolo’s bioinks for volumetric 3D printers, potentially bridging the gap between research and clinical applications in bioprinting. By combining xolo’s Xolography…
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Xolo Unveils Xube²: Newest Xolography 3D Bioprinter
Berlin-based company Xolo has announced the launch of its latest 3D printer, the Xube², utilizing their proprietary xolography technology. Building on the success of its predecessor, the Xube² promises to set new standards in the field of xolography additive manufacturing, offering unprecedented speed and precision. What is Xolography? Xolography is an innovative 3D printing technology…
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Further Research on 3D-Bioprinted Mini-Tumors At LACDR
Researchers at the Leiden Academic Centre for Drug Research(LACDR) have continued to test their models to enhance the testing and development of cancer immunotherapies. Using 3D bioprinting technology, they create mini-tumors in a collagen gel that closely mimics human tissue. This method allows them to observe real-time interactions between these mini-tumors and immune cells, providing…
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3D Bioprinting with Borate Bioactive Glass and Sodium Alginate
A recent study published in Science Direct highlights a new idea of integrating borate bioactive glass (BBG) with sodium alginate (SA) to enhances both printing precision and biocompatibility. This development has potential value for the creation of complex biological structures, including bone and soft tissue implants. Figure taken directly from publication. Sodium alginate, a natural…
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The Business of Biofabrication 